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19 Jan Theories on Microtubules’ Function in Thought

Microtubules in the Cytoskeleton

Microtubule Functions Continuing to look inside neurons for the knowledge storage and processing mechanisms, let’s consider what Microtubules do. Microtubules serve many clearly identified functions. These functions include acting as structural members of the cytoskeleton, providing cellular orientation, and guiding membrane and cytoplasmic movements. In addition to these known functions, there is evidence that suggests […]

27 Dec Microtubules

Microtubule Isozymes

Microtubules Neurons have hundreds of MT distributed in the soma and in the axon and dendrites. Microtubules, like IF, are filamentous organelles that form the cytoskeleton of neurons. Their cylindrical, composite polymers comprise part of the cytoskeletal infrastructure of cells. Their cylinders are long, and they possess a distinct polarity. Their surfaces are composed of spherical tubulin in columns […]

27 Dec Cytoskeleton Components in Cognition

Cytoskeleton

A Neuron’s Skeleton Unlike the external structure of many spheroid and amorphous cells, the external structure of neurons is complex and rigidly determined. As you may remember from earlier posts, the many different types of neurons residing in particular cortical strata (in layers of the gray and white matter) each have distinctive characteristics that enable […]

25 Dec Myelin Sheath Function: Insulators

Gray Matter White Matter CNS

Glial Cells Gray matter / white matter… what really matters? Glial cells form a white myelin sheath around axons and function as the nervous system‘s supporting actors. They are more numerous than neurons – there are over 100 billion neuroglia, many wrapped around the efferent (output) fibers of each nerve cell. They support impulse conduction by […]

24 Dec Neuron Components and Cybernetics

Neuron Organelles

What About Cybernetics? The properties of subcellular neuron components, also known as organelles, are important to this research because they might contribute to the information acquisition, storage, accessing and maintenance systems of the brain. I plan to further discuss the reason for separating storage and maintenance in a post in the section on cognition. These […]

22 Dec Modeling Neural Interconnections

Inside a Neuron

Neuron Branching The characteristic that distinguishes neurons from other types of cells is that they have things sticking out all over them. This phenomenon is called branching or arborization. While all cells are capable of sprouting appendages like cilia or dendrites, only some actually do. Cells that branch do so for specific reasons that are essential […]

01 Dec Robot Neurons: Analog versus Digital

Digital Brain

Digital is basically black and white: 1 is yes and 0 is no or vice-versa. Yet our world is full of other colors. We can efficiently use digital devices to stretch arbitrary numbers of 1’s and 0’s together to represent a virtually infinite degree of possible values. Yet there are places where exactly two values may […]

10 Nov Seeking a Universal Theory of Knowledge

Top Level Ontology

As a fundamental premise for this post, this blog as a whole, and my life’s work, I propose that language and “real world knowledge” are inextricably connected, and neither functions well without the other. This is why, in my opinion, natural language processing (NLP) initiatives focusing exclusively, or even primarily on language structure have significant […]

18 Sep Context is King Indeed

Knowledge Coordination Layer

There are many important innovations adding context to business processes and data to make information access, collaboration and analysis more effective. I just read another great perspective on context in collaboration showing how taxonomies add value to teams of knowledge workers. Adding context is especially needed in moving toward the knowledge enterprise. I contend that […]

15 Sep What is Inside Neurons?

Intracellular Structure of Neurons In earlier posts, we examined the brain, its areas, and the types of neurons that populate the different layers of some of the brain’s areas. In this post and more to follow, we will turn up the magnification and look a little deeper. What can be seen inside the cells? What […]